Generally, uric acid in the blood is low. When a high concentration is reported, it's called hyperuricemia. A high level of uric acid in the blood is responsible for gout
, an acute illness producing pain in one or more joints (often the big toe) but if the level remains high for a long time (months or years), the illness becomes chronic and causes debilitating joint pain and a loss of kidney function. Kidney stones can also be the result of uric acid in the blood.