Anti-inflammatories are medications which, by definition, fight inflammation. We differentiate steroidal anti-inflammatories, derived from cortisone, and non-steroidals which have no cortisone. They both have anti-inflammatory qualities then, but so do analgesics and antipyretics. They are used for certain chronic inflammatory rheumatisms and occasionally for pain, fever, and flu-like symptoms. The two most well-known molecules are aspirin and ibuprofen. Anti-inflammatories can have side-effects, notably gastro-intestinal, and must be used very carefully in people who have had an ulcer or are at risk of bleeding.