Bilirubin comes from the breakdown of the hemoglobin
in senescent red blood cells
in the spleen
. It is a yellow pigment responsible for the color of urine. It circulates in the blood
linked to a protein, albumin
, then is captured in the liver
and is excreted in the bile
, or yellowing, gives the skin a yellowish color, and is caused by a buildup of bilirubin in the blood. Too high a rate or a sudden increase of bilirubin in the blood may suggest an abnormal destruction of red blood cells, hepatitis, or cirrhosis
of the liver. Bilirubin mainly exists in two forms: the so-called free bilirubin is toxic and is transformed by the liver into so-called conjugated bilirubin
which is then eliminated through the urine and fecal matter.
Published by Jeff
Latest update on December 11, 2013 at 04:04 AM by Jeff.