Necrosis is when one or many tissue cells of the human body stop functioning through unnatural causes. This phenomenon usually occurs in areas where the blood has stopped circulating, such as in cases of myocardial infarction
, cerebral infarction or ischemic stroke
, or skin lesions. The necrotic cells are no longer able to function normally in the body, and are effectively dead. Depending on the area affected by necrosis, the consequences for the patient can go from mild to severe. Necrosis of the heart, for example, causes heart failure
, and necrosis of the brain cells can lead to mobility and sense impairment.