Cytomegalovirus or CMV is a normally harmless viral infection, but can be serious for immunocompromised individuals. It is common in people with HIV in the advanced stages of the disease. Very often in individuals without other pathologies, infection with this virus goes undetected or simply appears as fatigue. Sometimes, the affected individual may experience fever and general pain. In HIV patients, however, it is a potentially serious infection which often results in an impairment of the retina, and digestive or neurological inflammation. The treatment uses antivirals.