Transferrin - Definition

July 2017


Definition


Transferrin is a protein found in the blood that primarily serves to transport iron around the body. It is a modulator, and is able to readjust the amount of iron circulating in the blood depending on the needs of the body. Usually only a third of the transferrin in the blood circulates bound to a molecule of iron. The concentration of an indicator called transferrin saturation (TSAT), an assessment of the percentage of transferrin bound to iron in a blood sample, can therefore reveal the amount of iron present in the body. If this level decreases, other conditions can be suspected, notably hemochromatosis, a significant overload of iron in the body caused by a genetic anomaly.

Related

Original article published by . Translated by Jeff. Latest update on November 12, 2013 at 05:53 AM by Jeff.
This document, titled "Transferrin - Definition," is available under the Creative Commons license. Any copy, reuse, or modification of the content should be sufficiently credited to CCM Health (health.ccm.net).