Erythema multiforme is a skin disease whose exact cause is currently unknown, and which appears in the form of several outbreaks especially among men aged 20 to 40 years. The lesions appear as small, red elevations of the skin, sometimes bullous in appearance and usually appearing on the hands, forearms, knees, elbows, palms and soles of the feet, sometimes the scalp. It appears more severe following a herpes infection or relapse, and sometimes following other infectious diseases. In the case of an infection, the cause must be treated. Erythema multiforme usually heals spontaneously after a few outbreaks.