Enlarged red blood cells - Definition

March 2017


Definition


When red blood cells, which make up the blood and carry oxygen from the lungs to other cells, are too large, it is called macrocytosis . Macrocytosis is an abnormality in the blood that is characterized by the presence of macrocytes, red blood cells whose size and volume have increased. Macrocytosis is generally associated with the presence of anemia, a decreased number of red blood cells, and this decreases oxygenation of organs and tissues. The symptoms may be those of anemia with fatigue, paleness, increased heart rate, dizziness, shortness of breath ... It can be due to a deficiency of vitamin B12 or folate, vitamin B9, which leads to a defect in the formation of red blood cells which become larger. A vitamin B12 or folate supplement, in this case, can handle the macrocytosis. Macrocytosis is sometimes observed in chronic alcoholism, in certain abnormalities in the bone marrow, or due to certain medications.

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