Lactic acidosis - Definition

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Lactic acidosis is a serious complication of diabetes corresponding to an excessive accumulation of lactic acid in the blood. It essentially occurs in a diabetic person who also suffers from liver or kidney problems. Lactic acidosis causes muscle cramps, abdominal pain associated with digestive problems such as diarrhea, vomiting, asthenia (general fatigue), shortness of breath, and sometimes confusion that can lead to a coma. Lactic acidosis is fatal in 50% of the cases. Fortunately, it is relatively rare and almost exclusively concerns patients who have been treated with biguanides.