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Sideroblastic anemia - Definition


Sideroblastic anemia is caused by an insufficient amount of heme in the hemoglobin. The problem comes from the bone marrow or when the sideroblasts, cells that are responsible for making red blood cells, are abnormal with too much iron; this anomaly in the making of heme is the result, and is responsible for sideroblastic anemia. The origin can be hereditary, linked to a genetic anomaly or acquired from a malfunction in the production of red blood cells. Otherwise, sideroblastic anemia can also be toxic in origin as in the case of saturnism, or lead poisoning.