Antinuclear antibodies - Definition

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An antinuclear antibody is a variety of antibody that acts against the antigens situated on the surface of the nucleus of cells. Antinuclear antibodies are probably auto-antibodies, meaning antibodies that react with antigens from the same organism. The presence of antinuclear antibodies leads to auto-immune diseases, meaning that the antibodies attack the healthy cells of the individual. Antinuclear antibodies can be found in the case of viral infections, auto-immune diseases such as systemic lupus erythematosus, intoxications like chronic hepatitis, or inflammatory diseases.