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Neurofibroma - Definition


A neurofibroma is a tumor located on the peripheral nerves. It is caused by an uncontrolled growth of different cells forming the fascia, a layer of supportive connective tissue surrounding the peripheral nerves. Neurofibromas differ from neuromas in that the latter develop from Schwann cells. Hereditary genetic diseases are the principal cause for neurofibromas, and are classified as neurofibromatosis. The most classic example is neurofibromatosis type 1, formerly known as the von Recklinghausen disease, or neurofibromatosis, which presents with different sites of small-size tumors. The presence of neurofibromas can have mild to severe consequences depending on their size and location in the body.