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Low alkaline phosphatase - Definition


Alkaline phosphatase is an enzyme, that is to say a type of protein that enables chemical reactions, present in the blood in specific concentrations that are often analyzed and measured in order to diagnose various diseases, particularly those of the liver and bone. Low concentrations of alkaline phosphatase therefore often indicate seriously impaired liver function, which is called hepatocellular dysfunction, due to many different conditions, such as cirrhosis, a disease that causes the destruction of liver cells; or hepatitis, signifying liver inflammation. Hypophosphatasia is a hereditary disease that is characterized by a significant decrease in alkaline phosphate levels.