D-dimers - Definition

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D-dimers are what remains after the destruction of fibrin, a protein produced mainly in blood clotting. The presence of D-dimer in the blood is normal, but at low levels, and this information allows, in the case of significant increase of its levels, to detect the presence of a thrombus, or blood clot. D-dimers are well-proportioned and increase when venous thrombosis or a pulmonary embolism is suspected. However, D-dimers are not particular, and are increased in many other cases (in the elderly, for certain infections, or in pregnant women): low levels of D-dimers certainly eliminates thrombosis, but a high level does not guarantee its presence.