UC - Ulcerative colitis - Definition

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Ulcerative colitis (UC) is a chronic inflammation of the intestine, notably associated with Crohn's disease and Inflammatory Bowel Disease (IBD). On average, UC affects 3 times more women than men, with inflammation beginning at the mucous membrane of the rectum then progressively spreading to cover the rest of the colon. This disease progresses in the form of successive flare-ups, with potential secondary complications such as colon cancer. Ulcerative colitis can be indicated by red blood discharge from the rectum, abdominal pain, and diarrhea, with diagnosis requiring confirmation by visual examination of the digestive mucous membranes in these organs by rectal colonoscopy. Certain types of medication can improve the condition, such as sulfasalazine, corticosteroids, or immunosuppressives, but surgery is sometimes necessary.