Severe sepsis - Definition

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Severe sepsis is defined as a serious infectious syndrome secondary to a general infection that then spreads from the initial site to the rest of the body through the bloodstream. Sepsis is only qualified as severe if the blood pressure drops or an organ fails secondary to the resulting drop in perfusion. The affected organ can be the brain, in which case neurological symptoms, such as impaired consciousness, urinary elimination dysfunction indicating a kidney problem, respiratory distress, renal impairment, and others are observed. Clinical and biological criteria have been outlined to define the presence of severe sepsis. Cases must be treated immediately, focusing on the different organ dysfunctions, administering IV fluids, and identifying the initial infection responsible and how to treat it. If the disease progresses it can result in septic shock.