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Extrapyramidal syndrome - Definition


Extrapyramidal syndrome is a neurological disease that manifests similarly to Parkinson's disease. It can be caused by a true presence of Parkinson's disease, secondary to degeneration of certain neurons in the brain, leading to dopamine deficiency, a neurotransmitter, although other causes, such as abnormally high levels of copper in the body (Wilson's disease), neuroleptic therapies, or other degenerative conditions affecting the nervous system can be the cause. Extrapyramidal syndrome causes different symptoms, with akinesia, that is slowing and limiting movement; and muscular stiffness, also called plastic rigidity. This is where on moving a muscle, usually tested on the arm, the muscle tends to give in in sudden jerky movements, and remains in the same position once the movement has stopped.