Portal vein thrombosis - Definition

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Portal vein thrombosis is a rare disease, characterized by the presence of a thrombus, most often a blood clot, in the portal vein. In its role in the circulatory system, the portal vein transports blood from the digestive organs and the spleen to the liver. Portal vein thrombosis can be secondary to a number of different conditions, notably blood abnormalities, such as deficiency of certain coagulating factors, or hyperviscosity of the blood following bone marrow disease, among others.