Thyroglobulin - Definition

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Thyroglobulin is a protein involved in the synthesis of thyroid hormones. It is found in the tiny vesicles inside the thyroid gland, which capture the iodine supplied by food. It is within this protein that iodine binds to another protein: tyrosine, involved in synthesizing the active hormones of the thyroid: T3 and T4. Thyroglobulin concentration can be assessed by blood test, and is an indicator of how the gland is functioning in certain cases of disease.