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Primary sclerosing cholangitis - Definition


Definition


Primary sclerosing cholangitis (PSC) is characterized by inflammation of the biliary passages, which constrict and prevent the normal flow of bile. In accumulating in the liver, it affects the hepatic cells. PSC sometimes evolves over the course of years without having any symptoms. When there are, they are most often jaundice, itching, and extreme fatigue accompanied by fever. The treatment of PSC consists of relieving these symptoms and taking prescribed medications intended to improve the bile flow. In the most severe cases, a liver transplant may be needed.
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