G6PD - Glucose-6-phosphate dehydrogenase deficiency - Definition

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A glucose-6-phosphate dehydrogenase deficiency (G6PD) is also called favism. It is an enzymatic deficiency characterized by the destruction of a part of the red blood corpuscles (red blood cells) and is fairly frequent. However, numerous people who display a glucose-6-phosphate dehydrogenase deficiency are not truly sick, and under the conditions that they do not consume broad beans and do not undergo antimalarial treatment, they may lead a perfectly normal life. Others, however, may display risks of hemolysis, characterized by serious anemia and icterus (jaundice) in affected newborns. This deficiency is especially present in Mediterranean countries.