Median lethal dose - Definition

Ask a question

Definition


The median lethal dose is a measure indicative of the rate of toxicity of a substance or an irradiation. For example, in the abbreviation DL50, the substance mass is capable of killing by ingestion 50% of test subjects in the conditions precisely indicated. These subjects are generally laboratory animals such as rats or mice. The median lethal dose is expressed in grams of active material per kilogram of the test subject. It can also be used as an inhaled substance, but in this case it is called a lethal concentration.