Hypoplasia - Definition

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Hypoplasia signifies the insufficient growth of tissue or an organ. The different possible forms include pulmonary, thyroid, and breast hypoplasia. This condition was first described in 1870 by Rudolph Virchow, and is typically genetic in origin, although toxicological causes have been proposed. Exposure of an embryo to chemical or medicinal substances is therefore known to cause deformations that can lead to hypoplasia.