Fundic gastritis - Definition

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Fundic gastritis is a form of chronic gastritis. This disease is an inflammation of the lining of the stomach affecting the fundus, meaning the large protuberance of the stomach in its first part. It has the characteristics of atrophic gastritis, meaning the atrophy of the surface layer of the stomach wall, and also the destruction of glands normally contained in the wall. This leads to decreased absorption of nutrients including vitamin B12 which sometimes causes pernicious anemia (or Biermer's anemia). This disease is responsible for anemia managed by vitamin B12 injections every month.