Factor V Leiden - Definition

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Factor V is a protein which is composed of the blood plasma which enters into the blood clotting process. There is a hereditary abnormality of the mutation of the factor V gene, called factor V Leiden, which is responsible for coagulation disorders. This abnormality causes accelerated blood clotting and an exaggerated blood thrombus formation, which increases the risk of developing thromboembolic disease, of the thrombosis type, in the lower limbs, stroke, or myocardial infarction. This anomaly is suspected in cases of unusually frequent or early thrombosis in the patient's life, and a blood test will enable research of this genetic abnormality, if necessary, with the agreement of the patient.