Elevated ferritin - Definition

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Ferritin is a protein that stores iron mainly in the liver, but also in the spleen and bone marrow... It therefore helps regulate the concentration of iron circulating in the body and its blood level called serum ferritin provides an assessment of the amount of iron in reserve. In the case of a decrease in serum ferritin, iron deficiency or blood loss may be suspected. In contrast, when there is a rise in serum ferritin, many causes can be considered: these are disorders in the regulation of iron such as hemochromatosis, certain inflammatory diseases, the destruction of liver cells during hepatitis, which releases iron, or cancers in the liver, kidney, lung, pancreas, or breast. This increase can also be a symptom of leukemia or lymphoma, such as Hodgkin's disease.