Estradiol - Definition

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Estradiol (or oestradiol) is the principal active hormone of the three natural estrogens in a woman (the other two being estriol and estrone). This sexual hormone is secreted by the ovaries, and its rate increases noticeably during ovulation, then diminishes in the second phase of the menstrual cycle. Estradiol fulfills numerous hormonal functions: development of the breasts and genital organs, improvement of bone density, and lipid supply during puberty.