IGF-1 - Definition

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Insulin-like growth factor, or more simply IGF-1, denotes peptide hormones that have a similar chemical structure to that of insulin. The secretion of these hormones by the liver is stimulated by growth hormone (GH), after which they are carried throughout the body via the circulatory system. This hormone acts on the production of cartilage lining the long bone joints. Previously called somatomadin C, IGF-1 was defined for the first time in 1987 by a team of British researchers in collaboration with a French team.