Islets of Langerhans - Definition

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The islets of Langerhans are areas of the pancreas named after biologist Paul Langerhans who discovered them. These are endocrinal cells located in the pancreas, which synthesize hormones, such as glucagon, somatostatin, pancreatic polypeptide, and insulin. They lie in the epithelial cavities of the pancreas, and represent less than 2% of its total mass. Certain sufferers of Type 1 diabetes exhibit insufficient insulin production and can benefit, in some cases, from an islet of Langerhans transplant.