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Leukodystrophy - Definition


Definition


Leukodystrophy is a rare disease, usually genetic, characterized by a loss of myelin in the central and peripheral nervous system. Myelin is a substance present in the brain and spinal cord, which surrounds and protects nerves and enables a more rapid propagation of information. Symptoms appear in childhood, then gradually progress: motor disturbances, intellectual decline, loss of speech, and sensory loss. Various forms of leukodystrophies exist, and these rare diseases are part of the so-called orphan diseases. The ELA (European Leukodystrophy Association), sponsored by Zinedine Zidane, is involved in research and improving the quality of life of affected children.
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