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Cockroft-Gault formula - Definition


The Cockcroft-Gault formula allows, in medicine, the calculation of the estimated clearance and creatinine. The clearance is the ability of an organism, tissue, or organ, to eliminate fluid. In the kidney, creatinine is a good indicator for assessing the glomerular filtration rate, which measures kidney function in the roles of blood filtration and removal of unwanted substances. The results of these calculations using this formula are used to detect kidney failure and quantify its severity. It depends on the patient's age, sex, weight, and creatininemia, the levels of creatinine in the blood. Under certain conditions, including in the elderly, another formula called MDRD would be more reliable to estimate kidney function.