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Von Willebrand disease - Definition


Von Willebrand disease is an inherited disorder characterized by a deficiency in a clotting factor, the von Willebrand factor. It appears in childhood and is characterized by frequent bleeding, taking the form of easy gingivorrhagia when brushing teeth for example, nosebleeds, bruising of the skin, and often bleeding in the joints, called hemarthrosis. Given these symptoms, a blood test with analysis of coagulation factors enables the diagnosis and the qualitative and quantitative study of the von Willebrand factor. The form thus identified will determine the treatment to be adopted, either with the use of a molecule, desmopressin, or transfusion of the missing coagulation factors.