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Metformin (Glucophage®) - Definition


Metformin, sold especially under the name Glucophage® or Stagid®, is an antidiabetic drug in the biguanide family, taken in the form of tablets. It is used to treat chronic hyperglycemia, the abnormal elevation of glucose in the blood as part of the development of diabetes mellitus type 2, meaning a side-effect of the resistance of the cells to the action of insulin (insulin resistance), a hormone secreted by the pancreas and playing a role in controlling blood sugar. It is mainly used when a suitable diet failed to lower glucose to desirable levels. This drug enables the re-establishment of the glycemic balance by reducing insuilnoresistance, and reducing diabetic complications.