Amyloid disease

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Amyloid disease is a disease characterized by deposits of a protein similar to amylose. In general, amyloid diseases are responsible for amyloid deposits in various organs or tissues. Depending on the form, deposits can be restricted to a specific organ or affect several organs or all of the body. They can be congenital, secondary to a disease such as tuberculosis or cancer, or occur as a result of an abnormal blood protein proliferation. In the case of amyloid neuropathy, deposits are made in the nerves and the patient is gradually invalidated and experiences widely varying symptoms related to the dysfunction of peripheral nerves. Hereditary forms of this neuropathy exist. Generally, amyloidosis can be deadly in just a few years.


Symptoms of amyloid disease are varied and the symptoms depend on the organs affected by the deposits. The organs affected are mainly:
  • the heart;
  • skin;
  • peripheral nerves;
  • the digestive organs;
  • kidneys;
  • liver;
  • spleen;
  • muscles;
  • the nervous system (amyloid deposits involved in Alzheimer's disease).


Amyloid diseases are rare diseases and diagnosis can be done by highlighting the proliferation of a blood protein involved, or more often by examining cells from a biopsy of the affected organ. In some cases, the detection of a genetic mutation is possible.


Amyloid disease is generally detrimental and treatments can help slow the progression of the disease, but are different depending on the type of pathology identified.